Lisa Skinner, 52, blasted her estranged husband Bradley Skinner, 59, after he threatened her with a knife and a gun.
She was then struck by police gun fire when she did not immediately drop her own weapons.
He is now fighting for his life in hospital, whereas she is in a stable but critical condition, according to AL.com .
AL.COM /Landov / Barcroft Media
Mrs Skinner, who believed her husband wanted to make her the victim of a murder/suicide, armed herself with a shotgun then went into the garage.
He followed her and aimed his pistol at her.
She then opened fire with a shotgun, hitting him in the chest.
AL.COM /Landov / Barcroft Media
Officers from Huntsville police arrived on scene and heard gunshots ring out and saw Mrs Skinner in the garage holding the shotgun.
They demanded she drop her weapon but when she turned toward them with the gun in her hand, at least one officer fired at her, wounding, but not killing her.
Both she and her husband were taken to Huntsville Hospital.
Madison County Jail
Several neighbors reportedly heard the gunfire on the normally quiet street, according to AL.com.
Neighbour Angela Humlicek, who lives across the street, said she heard a single shot and, when she went to see what the noise was, she helped the woman's mother to safety.
Records show science teacher Mrs Skinner had several restraining orders against her estranged husband, according to WHNT 19 News, and lived in fear of violence from him.
Mrs Skinner's petitions to the court describe her estranged husband, who she was divorcing after almost 11 years, as a "clever, gifted manipulator" who was heavily armed.
AL.COM /Landov / Barcroft Media
He was arrested on February 21 on charges of harassing communications and domestic violence by harassment.
Mrs Skinner described him as a "mercurial" man who abused alcohol and prescription and illegal drugs and said he had begun speaking about his death.
She wrote: "On [February 18] he began talking about dying and had often mentioned that he wanted to 'take out all of his enemies and die by PoPo,' meaning he wished the police would kill him after he had killed his enemies.
"I am certainly now an enemy."
AL.COM /Landov / Barcroft Media
"I left in fear of becoming a victim of murder/suicide," she wrote.
And as recently as Friday, Mr Skinner had been ordered - again - to have no contact with his estranged wife or her family.
He was also ordered to undergo a psychiatric evaluation prior to a court hearing next month in the couple's divorce.
Meanwhile, the officer who shot the woman has been placed on administrative leave.
AL.COM /Landov / Barcroft Media
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